The Metabolome of Wheat Fungal (Fusarium) Disease Database (MWFD)

The Metabolome of Wheat Fungal Disease Database lists metabolites that are present at higher concentrations during wheat’s response to Fusarium head blight and their:

  • Characteristics
  • Chemical similarities
  • Known targets
  • Hypothetical targets in Wheat and Fusarium

Fungal diseases are an increasing threat to wheat production and worldwide food security due to changing climate, altered agricultural practices and increasing demand. Fusarium headblight is a devastating disease of bread wheat (Triticum aestivum) primarily caused by the fungus Fusarium Graminearum. Partial resistance to Fusarium head blight of several wheatcultivars includes specific metabolic responses to inoculation.

Previously published studies have determined some of the major metabolic changes induced by pathogens in resistant and susceptible plants. Although the mechanism of action for themajority of these metabolites and their role in resistance is unknown many have known targets in other species that can be used to determine possible targets in Fusarium.

MWFD is a project led by National Research Council of Canada as part of Canadian Wheat Alliance.